LIVING TISSUE MODEL DEVICE, VASCULAR WALL MODEL, VASCULAR WALL MODEL DEVICE AND METHOD OF EVALUATING TEST SUBSTANCE

摘要

The biological tissue model device comprises: a first liquid compartment storing a liquid composition; a second liquid compartment storing the liquid composition; and a cell stack disposed between the first liquid compartment and the second liquid compartment as a distribution compartment between the two compartments. The vessel wall model includes a porous membrane having a honeycomb structure; a vascular endothelial cell layer disposed on one surface of the porous membrane; and a smooth muscle cell layer or a mesenchymal stem cell layer disposed on the other surface of the porous membrane. The vessel wall model device comprises: a first liquid compartment storing a liquid composition; a second liquid compartment storing the liquid composition; and a blood vessel wall model disposed between the first liquid compartment and the second liquid compartment as a distribution compartment between the two compartments. Applications of these models or model arrangements are also provided.