Production of polyhydroxybutyrate in WOOD-LJUNGDAHL microorganisms

摘要

The present invention provides microorganisms and methods for the production of polyhydroxybutyrate (PHB) from a gaseous substrate. In particular, the present invention includes (a) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (b) an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and (c) 3-hydroxy Provided are non-naturally occurring Wood-Ljungdahl microorganisms and related methods comprising an enzyme that converts to oxybutyryl-CoA polyhydroxybutyrate.