The present invention relates to a practical clinical trial support system and method, the method according to the present invention for the patient screening criteria for clinical trials of the test drug, information on the control drug administered to the control and efficacy evaluation for the control drug administration Step of inputting clinical design conditions including clinical variable items, patient information of a trial group participating in a trial study to which a trial drug is administered, and a control group participating in a trial study to which a control drug is administered, determined to actually participate in the trial Step, extracting EMR control candidates satisfying the clinical trial design conditions from the EMR database storing the electronic medical records, and covariate distribution between the clinical trial control group and the clinical trial participation test group consisting of the EMR control candidate and the clinical trial participation control group And selecting a part of the EMR control candidates as a control patient through propensity score matching so that the similarity satisfies a predetermined criterion. The present invention reduces the target number of control patient recruitment required in a randomized clinical trial and reinforces the test result data collected in the actual situation to help in terms of validation, and in the case of rare diseases, it is very difficult to recruit control patients There is an advantage that it can serve as an easy reinforcement data in risk-benefit analysis for item approval by comparing and presenting the control group in.
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