NRLNeural retina leucine zipper siRNAAsymmetric siRNA Inhibiting Expression of NRL

摘要

The present invention relates to an asymmetric siRNA that suppresses the expression of a NRL (Neural retina leucine zipper) and its use, and more particularly, an antisense strand comprising a sequence complementary to an mRNA encoding NRL, and a complement to the antisense strand. It relates to an asymmetric siRNA comprising a sense strand forming a bond and a pharmaceutical composition for improving or treating retinal disease comprising the asymmetric siRNA.