miRNA17-5p Biomarker microRNA17-5p for predict metastasis of colorectal cancer and uses thereof

摘要

The present invention relates to a biomarker for predicting metastasis of colorectal cancer and its use, more specifically, a marker composition for predicting colorectal cancer metastasis, including microRNA17-5p (miRNA17-5p), measuring the expression level of the miRNA It relates to a composition for predicting colorectal cancer metastasis and a kit for predicting the colorectal cancer metastasis using the marker. By confirming that the miRNA17-5p according to the present invention directly binds to 3`UTR of Vimentin, an Epithelial Mesenchymal Transition (EMT)-related factor, which is an important process of metastasis in patients with colorectal cancer, and regulates expression, colon cancer is not It is expected to be useful as a biomarker for predicting metastasis to organs.