METHOD OF DETECTING CIRCULATING TUMOR CELL BY USING FERROFLUID IN MICROFLUIDIC CHANNEL AND MICROFLUIDIC CHIP THEREFOR

摘要

A tumor cell detection method for detecting tumor cells from blood samples comprising tumor cells and normal cells provides a microfluidic chip comprising two micro-separation channels and two magnetic field-forming portions provided adjacent to each micro-separation channel Step of providing a viscoelastic solution comprising a blood sample and a magnetic fluid to the first micro-separation channel through the inlet, the viscoelastic solution along the first micro-separation channel to pass through the periphery of the first magnetic field forming portion of the A first separation step of separating cells primarily according to particle size, a part of the viscoelastic solution introduced into the second fine separation channel passes through the second fine separation channel by allowing a part of the viscoelastic solution to pass through the periphery of the second magnetic field forming part And a second separation step of secondarily separating the tumor cells from the normal cells and collecting the tumor cells discharged through the outlet.