The composition for whitening comprising the extract of Daphne odora or a fraction thereof of the present invention can suppress melanin production and tyrosinase production without cytotoxicity, and thus a cosmetic composition for skin whitening, food composition, quasi-drug composition, It can be usefully used as a composition for external application for skin, a health functional food capable of preventing or alleviating skin pigmentation disease, or a therapeutic agent for skin pigmentation disease.
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