DNA Method of Evaluating Integrity of Cell-Free DNA

摘要

A cell-free DNA integrity evaluation method according to an embodiment of the present invention includes the steps of aligning the nucleotide sequence of the cell-free DNA to a standard genome; Analyzing the length distribution pattern of the cell-free DNA and the adenine base ratio at the 5'end; And evaluating the integrity of the cell-free DNA based on at least one of a length distribution pattern of the cell-free DNA and a ratio of adenine bases at the 5'end.