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METHODS AND SYSTEMS FOR EVALUATING DNA METHYLATION IN CELL-FREE DNA
METHODS AND SYSTEMS FOR EVALUATING DNA METHYLATION IN CELL-FREE DNA
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机译:用于评估无细胞DNA中DNA甲基化的方法和系统
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摘要
The present disclosure concerns embodiments related to methods of enriching particular DNA for analysis of methylation status and/or profiles, for example in the process of diagnosis of cancer. In particular embodiments, the methods utilize cell-free DNA as a source of DNA instead of genomic DNA and allow for focused enrichment of fragments having two or more enzyme digestion sites and containing at least one CpG site.
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