Methods of fluorinating filters for pipette tips, pipette tips, related manufacturing methods and pipettes

摘要

The present invention relates to a method of fluorinating a filter 26 for a pipette tip 20, wherein the filter 26 is made of a solid porous structure made of polyolefin. According to the present invention, the method comprises the steps of: (a) placing the filter 26 in an enclosure, (b) creating a vacuum in the enclosure, and (c) a fluorinating agent injected into the enclosure in a gaseous state. and comprising the step of contacting the filter (26), wherein the fluorinating agent is composed of a di-fluorine F _2, the de fluorine F ₂ is introduced into the enclosure at a partial pressure of 100 Pa to 10000 Pa, the steps (c) is carried out at a temperature of 0°C to 100°C. The present invention also relates to a pipette tip 20 comprising a filter 26 modified by the above fluorination method, a method of manufacturing such a tip 20, as well as a suction pipette having such a tip 20. .