Method for producing surface-modified exosomes from various cells

摘要

The present invention relates to a method for producing a surface-modified exosomes, etc. The method for producing an exosome according to the present invention is a cancer cell and through the metabolic glycoengineering (Metabolic glycoengineering) and bioorthogonal coppper-free click chemistry By modifying various cell surfaces such as stem cells and isolating the exosomes isolated therefrom, the exo ultimately contains physiologically active substances derived from donor cells but increases stability by the modified surface and has cancer cell specific target ability. Can provide some. Thus, exosomes prepared by the method according to the invention can be usefully used for cancer prevention, improvement, or treatment.