首页> 外国专利> TrioBP Biomarker composition for diagnosis of glioma comprising TRIO and F-actin-binding protein

TrioBP Biomarker composition for diagnosis of glioma comprising TRIO and F-actin-binding protein

机译:用于诊断神经胶质瘤的TrioBP生物标志物组合物,包含TRIO和F-肌动蛋白结合蛋白

摘要

The present invention relates to a biomarker composition for diagnosing glioma, comprising TrioBP, and a diagnostic composition, diagnostic kit, a method for providing information on glioma diagnosis, a method for screening a glioma therapeutic agent, and a pharmaceutical composition for preventing or treating glioma. . TrioBP of the present invention is overexpressed in glioma cells, and the effect of inhibiting cell proliferation and migration through the inhibition of the TrioBP is remarkably excellent, it is possible to diagnose glioma by targeting TrioBP as well as nerves using its inhibitor It is also available for screening, prophylaxis or treatment of glioma, which can be useful in related pharmaceutical and medical projects.
机译:本发明涉及用于诊断神经胶质瘤的生物标志物组合物,其包含TrioBP,诊断组合物,诊断试剂盒,提供关于神经胶质瘤诊断的信息的方法,用于筛选神经胶质瘤治疗剂的方法以及用于预防或治疗神经胶质瘤的药物组合物。 。 。本发明的TrioBP在神经胶质瘤细胞中过表达,并且通过抑制TrioBP而抑制细胞增殖和迁移的效果非常优异,使用其抑制剂通过靶向TrioBP和神经可以诊断神经胶质瘤。用于脑胶质瘤的筛查,预防或治疗,可用于相关的药物和医学项目。

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