3 HGF HGF Method for producing HGF using three-dimensional culture of salivary glandular stem cells and composition for preventing or treating xerostomia comprising HGF

摘要

The present invention relates to a method for producing HGF through three-dimensional culture of salivary gland stem cells and composition for the prevention or treatment of dry mouth comprising HGF as an active ingredient, in detail, three-dimensional culture of salivary gland stem cells or salivary gland progenitor cells It relates to a method for preventing or treating salivary gland dysfunction, especially dry mouth disease, including HGF production method and HGF as an active ingredient. Three-dimensional culture of salivary gland stem cells confirmed that the expression of HGF was increased compared to other active factors, through which HGF can be used to develop therapeutics for preventing and treating salivary gland dysfunction diseases, especially dry mouth. have.