- HYALURONIC ACID-FLAVONOID CONJUGATE NANOPARTICLE COMPRISING SAME AND MANUFACTURING METHOD THEREOF

摘要

One embodiment of the present invention relates to a hyaluronic acid-flavonoid conjugate conjugated by combining low molecular weight hyaluronic acid with a flavonoid and a nanoparticle comprising the same. Conjugates of low molecular weight hyaluronic acid and 7,8-dihydroflavone and nanoparticles comprising the same according to an embodiment of the present invention have the advantages of high biological absorption and affinity while simultaneously having the biological properties of the two components There is this. In addition, the conjugate and the nanoparticles have an excellent anticancer effect and collagen synthesis enhancing effect, and can be applied to a pharmaceutical composition or cosmetic composition for cancer prevention or treatment.