Biomarker for diagnosing or prognosis predicting of cholangiocarcinoma and use thereof

摘要

The present invention relates to a biomarker for diagnosis or prognosis of biliary tract cancer and its use, wherein TGFBI mRNA is highly expressed in biliary tract cancer tissue, TGFBI protein is specifically expressed in biliary tract cancer cell line, It was confirmed that the soluble TGFBI protein content was high and the prognosis of the patients with biliary tract cancer with high expression of the TGFBI gene was significantly poor through analysis of the gene database including prognostic information. Therefore, the TGFBI may be usefully used as a biomarker for diagnosing or prognosticting biliary tract cancer.