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A METHOD FOR PREPARING A STEM CELL SECRETING ANTI-INFLAMMATORY SUBSTANCES AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING CULTURE MEDIUM OF THE STEM CELL
A METHOD FOR PREPARING A STEM CELL SECRETING ANTI-INFLAMMATORY SUBSTANCES AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING CULTURE MEDIUM OF THE STEM CELL
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机译:一种制备包含干细胞培养培养基的干细胞分泌抗炎物质和抗炎组合物的方法
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摘要
One embodiment of the present invention provides a method for culturing umbilical cord blood-derived multipotent stem cells releasing anti-inflammatory components for improving and treating inflammatory diseases and an anti-inflammatory composition comprising the Joule's cell culture. Specifically, the anti-inflammatory component may inhibit the production of the inflammatory substances NO (Nitric Oxide) and PGE 2 (Prostaglandin E 2 ), and more specifically, inhibit the expression of genes and proteins of iNOS and COX2 related to the inflammatory substances. This can inhibit the production of pro-inflammatory agents.
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机译:本发明的一个实施方案提供了一种用于培养脐带血来源的多能干细胞的培养方法,该方法释放了用于改善和治疗炎性疾病的抗炎成分,以及一种包含焦耳氏细胞培养物的抗炎组合物。具体而言,抗炎成分可以抑制NO(一氧化氮)和PGE 2 Sub>(Prostaglandin E 2 Sub>)的产生,更具体地讲,抑制其表达iNOS和COX2的基因和蛋白质与炎症物质有关。这可以抑制促炎剂的产生。
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