METHODS AND COMPOSITIONS FOR IN VIVO INDUCTION OF PANCREATIC BETA CELL FORMATION

摘要

Embodiments of the invention include three levels of beta cell physiology: (i) glucose metabolism, (ii) membrane receptor function, and (iii) transcription leading to in vivo formation of beta cells in the pancreas for the purpose of treating diabetes. Stimulates factors. In certain aspects, the method comprises three levels of cell physiology: metabolism, membrane receptor function, and integration of gene transcription. The integration of multiple levels of cell physiology creates a synergistic effect on beta cell formation.