首页> 外国专利> 8--2-4--1345--6-543--6- SALTS AND POLYMORPHS OF 8-FLUORO-2-4-METHYLAMINOMETHYLPHENYL-1345-TETRAHYDRO-6H AZEPINO543-CDINDOL-6-ONE

8--2-4--1345--6-543--6- SALTS AND POLYMORPHS OF 8-FLUORO-2-4-METHYLAMINOMETHYLPHENYL-1345-TETRAHYDRO-6H AZEPINO543-CDINDOL-6-ONE

机译:8--2-4--1345--6-543--6- 8-氟-2--4-甲基亚氨基甲基]苯基-1345-四氢-6H叠氮基[543-CD]吲哚-6-的盐和多价

摘要

The present invention is 8-fluoro-2- {4-[(methylamino) methyl] phenyl} -1,3,4,5-tetrahydro-6H-azepino [5,4,3-cd] indole-6 -It relates to a new polymorph form of On and its manufacturing method. Such polymorphic forms can be components of pharmaceutical compositions and can be used to treat mammalian disease states mediated by poly (ADP-ribose) polymerase activity, including disease states such as cancer.
机译:本发明是8-氟-2- {4-[((甲基氨基)甲基]苯基] -1,3,4,5-四氢-6H-叠氮庚[5,4,3-cd]吲哚-6-到一种新的On的多晶型形式及其制造方法。这样的多晶型形式可以是药物组合物的成分,并且可以用于治疗由聚(ADP-核糖)聚合酶活性介导的哺乳动物疾病状态,包括诸如癌症的疾病状态。

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