PATIENT-DERIVED HEPATOCELLULAR CARCINOMA CELL LINES AND METHOD FOR SCREENING ANTICANCER AGENT USING SAME

摘要

The present invention relates to patient-derived hepatocellular carcinoma cell lines (AMC-H1, AMC-H2) and a method for screening an anticancer agent using the same. The patient-derived hepatocellular carcinoma cell lines according to the present invention not only exhibit characteristics of liver cancer cells but also can continuously secrete HBV DNA and thus, can be used as a very useful platform for research on the onset and treatment of liver cancer related to HBV infection. In addition, according to the present invention, the patient-derived hepatocellular carcinoma cell lines can be used to discover the optimal treatment agent and treatment method for liver cancer and can be applied to discover a novel target for liver cancer treatment.;COPYRIGHT KIPO 2020