Patient-derived hepatocellular carcinoma cell lines and the method for screening anticancer agents using thereof

摘要

The present invention relates to a patient-derived liver cancer cell line (AMC-H1, AMC-H2) and an anticancer agent screening method using the same. The patient-derived liver cancer cell lines AMC-H1 and AMC-H2 of the present invention not only exhibit the characteristics of liver cancer cells, but also can continuously secrete HBV DNA, and are very useful for research on the process and treatment of liver cancer associated with HBV infection. It is expected to be a platform. In addition, it is expected that the optimal treatment and treatment method for liver cancer using the patient-derived liver cancer cell line may be applied to discover new targets for treatment of liver cancer.