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3-- Novel method for preparing 3-amino-piperidine

机译：3--制备3-氨基-哌啶的新方法

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摘要

The present invention enables mass production of industrial scale with high quality optical purity of ( 3R,4R )-(1-benzyl-4-methylpiperidin-3-yl)methylamine , a key intermediate required for synthesizing tofacitinib. It relates to a manufacturing method.

机译：本发明使得能够大规模生产具有高光学纯度的（ 3R，4R ）-（1-苄基-4-甲基哌啶-3-基）甲胺，a 合成托法替尼所需的关键中间体。本发明涉及一种制造方法。 展开▼

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公开/公告号KR102131107B1

专利类型

公开/公告日2020-07-07

原文格式PDF

申请/专利权人 DASAN PHARMACEUTICAL CO. LTD.;
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申请/专利号KR20190005194

发明设计人 류형선;신동균;엄운용;이규혁;노경탁;이주철;
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申请日2019-01-15

分类号C07D211/56;A61K31/519;C07D487/04;

国家 KR

入库时间 2022-08-21 11:04:16

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机译：制备3-氨基哌啶二盐酸盐的单一对映体的方法

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机译：制备3-氨基-哌啶衍生物的方法

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