Composition for Assaying Activity of Uridine 5'-diphosphoglucuronosyltransferase Comprising Licoricidin and Use Thereof

摘要

The present invention relates to a composition for evaluating uridine 5`-diphosphoglucuronosyltransferase activity including lycoricidine and a method for evaluating the activity of the enzyme of a new drug candidate using the same. When the composition according to an embodiment of the present invention is used, uridine 5`-diphosphoglucuronosyltransferase activity including UGT1A9, a biphasic metabolic enzyme of a candidate substance necessary for drug evaluation during the course of developing a new drug candidate substance, It can be effectively measured and used to predict drug interactions in the body.