Composition for preventing ameliorating or treating stress or depression comprising flavonoid compound as effective component

摘要

The present invention relates to a composition for preventing, ameliorating or treating stress or depression comprising a flavonoid-based compound as an active ingredient, and more particularly, for the prevention or improvement of stress or depression comprising saponarin as an active ingredient It relates to a health functional food composition or a pharmaceutical composition. Saponarin of the present invention not only restores superoxide disproportionation enzyme and corticosterone to normal levels in an animal model of depression by administration of stress hormones, but also improves depression and anxiety behavior in tail suspension and forced swimming tests. As it is effective, it can be usefully used in manufacturing health functional foods or medicines for the prevention, improvement or treatment of stress or depression.