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METHOD FOR DIFFERENTIAL DIAGNOSIS OF INFECTIOUS MONONUCLEOSIS OF VARIOUS AETIOLOGY

机译:各种病因感染性单核细胞的鉴别诊断方法

摘要

FIELD: laboratory diagnostics.;SUBSTANCE: invention relates to laboratory diagnostics, medical virology, molecular biology and epidemiology and can be used for differential diagnosis of infectious mononucleosis associated with Epstein-Barr virus and human herpes virus type 6. Substance of the method: in peripheral leukocytes of patients diagnosed with infectious mononucleosis, FADD mRNA, CIRBP transcript 2 and TRAF3 transcript 2 levels are determined and if the expression is reduced, the EBV-associated is diagnosed, and if the expression increases, the HHV-6-associated infectious mononucleosis is diagnosed.;EFFECT: invention provides an informative and evidentiary method for differential diagnosis of infectious mononucleosis.;1 cl, 3 dwg, 2 tbl
机译:技术领域:本发明涉及实验室诊断,医学病毒学,分子生物学和流行病学,并且可以用于与爱泼斯坦-巴尔病毒和人疱疹病毒6型相关的传染性单核细胞增多症的鉴别诊断。确定被诊断为感染性单核细胞增多症,FADD mRNA,CIRBP转录本2和TRAF3转录本2水平的患者的外周血白细胞,如果表达降低,则诊断与EBV相关,如果表达增加,则说明与HHV-6相关的感染性单核细胞增多症效果:本发明提供了用于鉴别诊断传染性单核细胞增多症的有益和证据的方法。1cl,3 dwg,2 tbl

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