胃肠道间质瘤的靶点DEPDC5及其在诊断和治疗中的应用

摘要

The present invention provides a gastrointestinal stromal tumor target DEPDC5 and an application thereof in diagnosis and treatment. Specifically, provided is a use of a gene, mRNA, cDNA, or a protein of DEPDC5, or a detection reagent thereof for (i) serving as markers used to detect primary gastrointestinal stromal tumors or advanced gastrointestinal stromal tumors and/or (ii) preparing diagnostic reagents or kits used to detect primary gastrointestinal stromal tumors or advanced gastrointestinal stromal tumors. Further provided is an application of the DEPDC5 gene, a protein thereof, or an agonist thereof in the treatment of gastrointestinal stromal tumors.