SOLUTION INJECTABLE A PH 7 COMPRENANT AU MOINS UNE INSULINE BASALE DONT LE PI EST COMPRIS DE 5,8 A 8,5 ET UN CO-POLYAMINOACIDE PORTEUR DE CHARGES CARBOXYLATES ET DE RADICAUX HYDROPHOBES

摘要

The invention relates to a composition in the form of an injectable aqueous solution, the pH of which is between 6.0 and 8.0, and which comprises at least: c) a basal insulin having an isoelectric point pI of between 5.8 and 8.5; d) a copolyamino acid bearing carboxylate charges and hydrophobic radicals Hy, wherein said copolyamino acid consists of glutamic or aspartic units and said hydrophobic radicals Hy have the following formula I: (I). In one embodiment, the composition according to the invention is characterized in that it comprises from 40 to 500 U/ml of basal insulin having an isoelectric point of between 5.8 and 8.5.