MÉTHODES DE TRAITEMENT DE L'INSUFFISANCE CARDIAQUE EN UTILISANT DES ANTICORPS ANTAGONISTES DU RÉCEPTEUR AU GLUCAGON

摘要

The present disclosure relates to methods for treating or preventing heart failure using a glucagon receptor blocking agent. In various embodiments, the present disclosure relates to methods for treating or preventing heart failure (e.g., post-myocardial infarction heart failure), diabetic cardiomyopathy heart failure), and lateral ventricular (LV) remodeling, using antigen binding and antagonizing proteins, e.g., fully human antibodies, that specifically bind to and antagonize the function of the human glucagon receptor.