首页> 中国专利> 抗HLA-DQ2.5抗体

抗HLA-DQ2.5抗体

页面导航

摘要
著录项
相似文献

摘要

本发明提供抗HLA‑DQ2.5抗体。本发明的抗HLA‑DQ2.5抗体对HLA‑DQ2.5与谷蛋白肽形成的复合物具有结合活性，但对HLA‑DQ2.5与无关肽形成的复合物基本无结合活性。此外，发现本发明的抗体对T细胞活化具有抑制作用。

著录项

公开/公告号CN113950483A

专利类型发明专利
公开/公告日2022-01-18

原文格式PDF
申请/专利权人中外制药株式会社;
展开▼

申请/专利号CN202080039883.0
发明设计人大仓有生;高桥德行;津岛崇;祖尔卡尔奈恩·哈尔富丁;
展开▼

申请日2020-04-01
分类号C07K16/28(20060101);C07K16/16(20060101);C12N1/15(20060101);C12N1/19(20060101);C12N1/21(20060101);C12N5/10(20060101);C12N15/13(20060101);C12N15/63(20060101);C12P21/08(20060101);
代理机构11021 中科专利商标代理有限责任公司;
代理人柴云峰;张莹
地址日本国东京都
入库时间 2023-06-19 13:55:46

相似文献

专利
中文文献
外文文献

1. 抗HLA-DQ2.5抗体 [P] . 中国专利： CN113950483A . 2022-01-18
2. 抗CD3抗体、可活化抗CD3抗体、多特异性抗CD3抗体、多特异性可活化抗CD3抗体及其使用方法 [P] . 中国专利： CN107108738A . 2017-08-29
3. Anti-trkc agonist monoclonal antibody, anti-trkc antibody heavy chain, anti-trkc antibody light chain, murine anti-trkc antibody heavy chain, human anti-trkc antibody heavy chain, murine anti-trkc agonist antibody, agonist antibody human anti-trkc, isolated nucleic acid molecules, nucleic acid molecules, vector, host cell lines, hybridoma cell lines, host cell, polypeptide, pharmaceutical composition, method for treating neuropathy or neurodegenerative disease or repair of a injured nerve cell, method for increasing proliferation, maintenance or regeneration of peripheral neurons, method for treating disease or condition involving cell degeneration in a mammalian patient, angiogenesis induction method, method of manufacturing an anti-trkc antibody , uses of an antibody [P] . BR0112272A . 2003-05-06

机译：抗trkc激动剂单克隆抗体，抗trkc抗体重链，抗trkc抗体轻链，鼠抗trkc抗体重链，人源抗trkc抗体重链，鼠源抗trkc激动剂抗体，激动剂抗体人抗trkc ，分离的核酸分子，核酸分子，载体，宿主细胞系，杂交瘤细胞系，宿主细胞，多肽，药物组合物，治疗神经病或神经退行性疾病或损伤的神经细胞的修复方法，增加增殖，维持或增强的方法周围神经元的再生，用于治疗哺乳动物患者中涉及细胞变性的疾病或病症的方法，血管生成诱导方法，制造抗trkc抗体的方法，抗体的用途
4. METHODS FOR TREATING CANCER, FOR MANUFACTURING AN ANTI-ICOS ANTIBODY OR ANTIGEN BINDING PORTION OF THE SAME, FOR MANUFACTURING AN ANTIGEN ANTIBODY OF THE SAME, FOR MANUFACTURING AN ANTIGENO ANTIGENO ANTIGENO ANTIGENE OF THE SAME, ANTI-ICOS ANTIBODY OR ANTIGEN-BINDING FRAGMENT OF THE SAME AND AN ANTI-PD1 ANTIBODY OR ANTIGEN-BINDING FRAGMENT OF THE SAME, ANTI-ICOS ANTIBODY OR ANTI-ANTIGEN BINDING FRAGMENT OF THE SAME AND THE AGE OF OR ANTIGEN BINDING FRAGMENT OF THE SAME, USE OF AN ANTI-ICOS ANTIBODY OR ANTIGEN BINDING PORTION OF THE SAME AND ANTI-PD1 ANTIBODY OR ANTIGEN BINDING PORTION, POLYNUCLEOTIDE, VECTOR, AND, CÉPÉ [P] . BR112019025325A2 . 2020-06-23

机译：用于治疗癌症，制造相同抗体的抗-ICOS抗体或抗原的部分，制造相同抗体的方法，用于制造相同抗原的抗原-抗原抗原的抗原-抗原抗体的方法。相同抗体及其同一个抗PD1抗体或抗原结合片段，相同抗体的抗ICOS抗体或抗抗原结合片段以及相同抗体的年龄或与抗原结合的片段，使用抗-ICOS抗体或相同抗原结合部分和ANTI-PD1抗体或抗原结合部分，多核苷酸，矢量和CÉPÉ
5. a method for preventing or reducing norleukin incorporation and for producing a protein or polypeptide in a bacterial host cell, microorganism, anti-vegf antibody or anti-vegf antibody fragment, anti-factor d antibody or anti-factor antibody fragment anti-met antibody or anti-met antibody fragment [P] . BR112015005895A2 . 2017-12-12

机译：在细菌宿主细胞，微生物，抗-vegf抗体或抗-vegf抗体片段，抗d-d抗体或抗-因子抗体片段，抗-met抗体，抗met抗体片段