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一种用于评估HPV16疫苗免疫效果的阻断ELISA试剂盒

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摘要

本发明公开了一种特异性结合HPV16 E6蛋白的单克隆抗体及其应用。本发明还公开了应用本发明的单克隆抗体评估HPV16亚型疫苗免疫效果的试剂盒及其制备方法，该试剂盒采用阻断ELISA原理制备，有利于提高准确率，减少假阳性，为评估临床HPV16亚型疫苗免疫效果提供指导。

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公开/公告号CN108872593A

专利类型发明专利
公开/公告日2018-11-23

原文格式PDF
申请/专利权人北京索莱宝科技有限公司;
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申请/专利号CN201810726862.0
发明设计人王朋;马玉岭;白晓磊;刘希宇;
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申请日2018-07-04
分类号G01N33/68(20060101);G01N33/577(20060101);G01N33/558(20060101);
代理机构11508 北京维正专利代理有限公司;
代理人郑兴旺
地址 101102 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
入库时间 2023-06-19 07:23:16

法律信息

法律状态公告日

法律状态信息

法律状态
2018-12-18

实质审查的生效 IPC(主分类):G01N33/68 申请日:20180704

实质审查的生效
2018-11-23

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公开

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1. 一种用于评估HPV16疫苗免疫效果的阻断ELISA试剂盒 [P] . 中国专利： CN108872593A . 2018-11-23
2. 一种HPV16型E7蛋白的ELISA检测试剂盒 [P] . 中国专利： CN106610434A . 2017-05-03
3. The device of the elisa kit, based on an antigen: a protein m dbp, the ebv virus, particularly intended for the diagnosis of cancer serological npc, and the method of preparation of this protein [P] . 法国专利： FR2824912B1 . 2004-10-29

机译： Elisa试剂盒的装置基于一种抗原：一种蛋白m dbp，ebv病毒，特别是用于诊断癌症血清学npc的ebv病毒，以及该蛋白的制备方法
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机译：修饰的多聚核苷酸绝缘带，宿主细胞，分离的转基因非人类动物多肽，经过修饰以表达对ALK具有抗性的多肽突变体，与对ALK具有抗性的多肽突变体特异性结合的抗体，试剂盒p用于检测生物样品中对ALK抑制剂具有抗性的突变，以及用于评估生物样品为对ALK抑制剂具有抗性的突变的方法，用于诊断对至少一种对ALK抑制剂具有抗性或可能发展出抗性的癌症激酶小分子ALK，以评估Anto对ALK抑制剂具有抗性的突变的生物样品。用于诊断对至少一种激酶小分子ALK抑制剂具有抗药性或可能产生抗性的癌症，以评估该生物样品作为对ALK抑制剂有抗性的突变，即对狄诺司他抗性或可能对PF产生抗药性的癌症-02341066
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机译：治疗或预防或预防乳腺癌，检测，诊断和/或评估或预后乳腺癌，监测和/或评估乳腺癌治疗，鉴定是否存在乳腺癌细胞转移性乳腺癌的方法生物样品并用于评估或鉴定化合物，一种或多种bcmps，组合物，抗体，核酸和与一种或多种bcmps相互作用或调节其活性的试剂，疫苗，组合物，试剂盒和抗体的用途