首页> 中国专利> 人血管内皮生长因子与颗粒酶B融合蛋白的纯化及应用

人血管内皮生长因子与颗粒酶B融合蛋白的纯化及应用

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摘要

采用基因重组技术对血管内皮生长因子(VEGF)

著录项

公开/公告号CN1465702A

专利类型发明专利
公开/公告日2004-01-07

原文格式PDF
申请/专利权人曾位森;
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申请/专利号CN02124581.9
发明设计人曾位森;
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申请日2002-06-21
分类号C12N15/52;C12N15/63;C07K14/435;C07K19/00;A61K38/17;A61K48/00;
代理机构
代理人
地址 510515 广东省广州市同和第一军医大学细胞生物学与医学遗传学教研室
入库时间 2023-12-17 15:05:30

法律信息

法律状态公告日

法律状态信息

法律状态
2007-03-07

发明专利申请公布后的视为撤回

发明专利申请公布后的视为撤回
2005-08-24

实质审查的生效

实质审查的生效
2004-01-07

公开

公开

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1. 人血管内皮生长因子与颗粒酶B融合蛋白的纯化及应用 [P] . 中国专利： CN1465702A . 2004-01-07
2. 重组人血管内皮生长因子受体-抗体融合蛋白的纯化方法 [P] . 中国专利： CN105175548A . 2015-12-23
3. Fusion protein Fusion protein The soluble composition of the host cell material Process to generate a neutralizing anti-toxin directed against Clostridium botulinum toxin type A antibody to purify a recombinant fusion protein derived from a Clostridium botulinum toxin type A process to generate an antitoxin neutralizing directed against clostridium difficile toxin type b antibody treatment process process to generate a neutralizing antitoxin directed against clostridium difficile type a toxin composition process to vaccinate an individual to produce neutralizing antitoxin directed against clostridium difficile toxin processing the detection of clostridium antigens difficile in an ample process of purification of toxins from clostridium difficile from a culture and process of generation of a solid dosage form of a bird antitoxin directed against a protein of clostridial toxin [P] . BR9509903A . 1997-11-25

机译：融合蛋白融合蛋白宿主细胞材料的可溶性组成物产生针对A型肉毒梭菌毒素的中和抗毒素的过程纯化源自A型肉毒杆菌毒素的重组融合蛋白的抗体产生针对人肉毒杆菌的抗毒素的过程B型艰难梭菌毒素抗体处理工艺过程，产生针对A艰难梭菌毒素的中和抗毒素组合物，对个体进行疫苗接种，以生产针对艰难梭菌毒素的中和抗毒素，在充足的纯化纯化过程中检测艰难梭菌抗原来源于梭状芽胞杆菌毒素蛋白的鸟抗毒素固体剂型的培养物和固体剂型产生过程中的艰难梭菌毒素
4. A fusion protein Tioredoxina - Human glutamate decarboxylase 65 and inmunoquimicamente Enzymatic Active, the procedure for obtaining the Recombinant Fusion Protein from E.Coli, the same Protein including Biotin, and the methods that apply these Measuring products in human serum Antibodies against glutamate decarboxylase,Useful in the Early Detection of insulin dependent diabetes mellitus and forms of autoimmune diabetes in adults [P] . AR004784A1 . 1999-03-10

机译：融合蛋白Tioredoxina-人谷氨酸脱羧酶65和免疫quimicamente酶活性物质，从大肠杆菌获得重组融合蛋白的过程，包括生物素在内的相同蛋白以及将这些测量产品应用于人血清的方法抗谷氨酸脱羧酶抗体早期发现胰岛素依赖型糖尿病和自身免疫性糖尿病的形式
5. Eukaryotic expression vector, coding human angiopoietin-1 and the human vascular endothelium growth factor, method for producing it and application [P] . PL406839A1 . 2015-07-20

机译：编码人血管生成素-1和人血管内皮生长因子的真核表达载体，其制备方法和应用