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肿瘤早查初筛试剂

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摘要

肿瘤早查初筛试剂,包括试剂A和试剂B,试剂A每100毫升中含有邻联甲苯胺0.4～0.6克、酚酞0.5～1.0克、1%～2%的硫酸溶液1.0～2.0毫升、甲苯1.0～1.5毫升、75%～95%的乙醇40～60毫升,其余为80%～100%的乙酸,试剂B为2.0%～4.0%的双氧水。使用时,两试剂按1∶1配制即成检测液。本发明所提供的试剂具有操作简便、试剂稳定、抗干扰性强等优点,而且灵敏度适中,结果准确。

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公开/公告号CN1281148A

专利类型发明专利
公开/公告日2001-01-24

原文格式PDF
申请/专利权人北京三早生物工程技术有限公司;
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申请/专利号CN99109837.4
发明设计人周剑池;
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申请日1999-07-16
分类号G01N33/52;G01N33/574;
代理机构
代理人
地址 100034 北京市西城区平安里太平仓胡同甲一号1号楼241室
入库时间 2023-12-17 13:46:10

法律信息

法律状态公告日

法律状态信息

法律状态
2003-04-09

发明专利申请公布后的视为撤回

发明专利申请公布后的视为撤回
2001-01-24

公开

公开

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专利
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1. 肿瘤早查初筛试剂 [P] . 中国专利： CN1281148A . 2001-01-24
2. 妇科肿瘤早查盒 [P] . 中国专利： CN2393494Y . 2000.08.30
3. process of radionuclide labeling of murine or human, monoclonal or polyclonal anti-tumor necrosis factor associated with diseases whose pathophysiology involves tumor necrosis factor; reagent for diagnosis "in vivo" and / or "in vitro" based on murine or human antibodies, monoclonal or polyclonal anti-tumor necrosis factor associated with radionuclides; diagnostic methods "in vitro" and / or "in vivo" of diseases whose physiotopagenia involves tumor necrosis factor using the reagent thus obtained and kit for diagnosing diseases whose pathophysiology involves tumor necrosis factor based on said reagent [P] . BRPI1003970B1 . 2020-05-05

机译：与病理生理涉及肿瘤坏死因子的疾病相关的鼠类或人，单克隆或多克隆抗肿瘤坏死因子的放射性核素标记过程;基于鼠或人抗体，与放射性核素有关的单克隆或多克隆抗肿瘤坏死因子的“体内”和/或“体外”诊断试剂;使用如此获得的试剂的生理失常涉及肿瘤坏死因子的疾病的“体外”和/或“体内”诊断方法以及基于所述试剂的病理生理涉及肿瘤坏死因子的疾病的诊断试剂盒
4. radionuclide labeling process for murine or human monoclonal or polyclonal anti-tumor necrosis factor-associated antibodies to diseases whose pathophysiology involves tumor necrosis factor; "in vivo" and / or "in vitro" diagnostic reagent based on murine or human, monoclonal or polyclonal anti-tumor necrosis factor-associated antibodies to radionuclides; "In vitro" and / or "in vivo" diagnostic methods for diseases whose pathophysiology involves tumor necrosis factor using the reagent thus obtained and a kit for the diagnosis of diseases whose pathophysiology involves tumor necrosis factor based on said reagent [P] . BRPI1003970A2 . 2012-06-12

机译：鼠或人单克隆或多克隆抗肿瘤坏死因子相关抗体对病理生理学涉及肿瘤坏死因子的疾病的放射性核素标记过程;基于鼠或人，单克隆或多克隆抗肿瘤坏死因子相关抗体的“体内”和/或“体外”诊断试剂;使用如此获得的试剂对病理生理涉及肿瘤坏死因子的疾病的“体外”和/或“体内”诊断方法，以及基于所述试剂的病理生理涉及肿瘤坏死因子的疾病的试剂盒
5. METHOD FOR LABELLING WITH RADIONUCLIDES MURINE OR HUMAN, MONOCLONAL OR POLYCLONAL ANTI-TUMOUR NECROSIS FACTOR ANTIBODIES ASSOCIATED WITH DISEASES WITH PHYSIOPATHOGENESIS INVOLVING TUMOR NECROSIS FACTOR; REAGENT FOR IN VIVO AND/OR IN VITRO DIAGNOSIS ON THE BASIS OF MURINE OR HUMAN, MONOCLONAL OR POLYCLONAL ANTI-TUMOR NECROSIS FACTOR ANTIBODIES LINKED TO RADIONUCLIDES; METHODS FOR DIAGNOSING IN VITRO AND/OR IN VIVO DISEASES WITH PHYSIOPATHOGENESIS INVOLVING THE TUMOUR NECROSIS FACTOR, USING THE THUS OBTAINED REAGENT, AND KIT CONTAINING SAID REAGENT FOR DIAGNOSING DISEASES WITH PHYSIOPATHOGENESIS INVOLVING THE TUMOUR NECROSIS FACTOR [P] . 世界知识产权组织专利： WO2012054997A1 . 2012-05-03

机译：用放射性核素标记鼠或人，单克隆或多克隆抗肿瘤坏死因子抗体与涉及肿瘤坏死因子的光致病性疾病相关的抗体的方法;根据与放射性核素相连的鼠或人，单克隆或多克隆抗肿瘤坏死因子抗体对活体和/或活体诊断的试剂;诊断与肿瘤致病因素有关的，具有病理病理性疾病的和/或体内疾病的方法，使用上述获得的试剂，并包含用于诊断疾病的诊断性疾病的试剂盒。肿瘤坏死因子

1. 静脉"出事",早防早查并早治 [J] . 景在平 ,辛群 . 家庭医药 . 2007,第009期

2. 高通量抗生素残留初筛试剂盒的研制及应用 [J] . 范维 ,高晓月 ,李贺楠 . 食品科学 . 2019,第014期

3. 3种APTT试剂对LA的初筛价值 [J] . 付璐 ,李洁 ,董丽梅 . 检验医学 . 2019,第009期

4. 用两种HIV抗体试剂进行HIV初筛检测的效果对比 [J] . 陈新艳 . 当代医药论丛 . 2018,第007期

5. 国产和进口ELISA试剂HIV初筛结果与确证结果对比分析 [J] . 李敏 ,韩晓燕 ,朱建民 . 实验与检验医学 . 2018,第004期

6. HIV抗体初筛阳性样本三种初筛试剂复检与确认试验结果的对比分析 [C] . 刘淑琴 ,薛芳 . 纪念中国国际旅行卫生保健创建10周年暨中国卫生检疫创建130周年学术会议 . 2006

7. 新型类查尔酮DesmosdumotinC、查尔酮FMC衍生物的设计合成及其体外抗肿瘤研究 [A] . 梁海 . 2015

1. Simple chalcones and bis-chalcones ethers as possible pleiotropic agents [J] . Liargkova Thalia, Hadjipavlou-Litina Dimitra J., Koukoulitsa Caterina, Journal of enzyme inhibition and medicinal chemistry. . 2016,第2期

机译：简单的查耳酮和双查耳酮醚作为多效试剂

2. Simple chalcones and bis -chalcones ethers as possible pleiotropic agents [J] . Thalia Liargkova, Dimitra J. Hadjipavlou-Litina, Caterina Koukoulitsa, Journal of enzyme inhibition and medicinal chemistry. . 2016,第2期

机译：简单的查耳酮和双查耳酮醚作为多效试剂

3. Revisit: Eaton's reagent catalyzed synthesis of mono and bis-chalcone derivatives [J] . Tupare S.A., Nalage S.V., Bobe S.R., Letters in organic chemistry . 2012,第7期

机译：复习：伊顿试剂催化的单查尔酮和双查尔酮衍生物的合成

4. The importance of tumor metabolism in cancer prognosis and therapy; pre-clinical studies onrodent tumors with agents that improve tumor oxygenation [C] . Marion Stubbs, Simon P. Robinson, Chuk Hui, International Symposium on Regulation of Enzyme Activity and Synthesis in Normal and Neoplastic Tissues . 2003

机译：肿瘤新陈代谢在癌症预后和治疗中的重要性;临床前研究具有改善肿瘤氧合的试剂的肿瘤肿瘤

5. Ancient Lamprey VLR Antibodies as Tumor Diagnostic and Tumor Targeting Reagents. [D] . Nakahara, Hirotomo. 2017

机译：Ancient Lamprey VLR抗体作为肿瘤诊断和肿瘤靶向试剂。

6. α-Fluoro-α-nitro(phenylsulfonyl)methane as a fluoromethyl pronucleophile: Efficient stereoselective Michael addition to chalcones [O] . G. K. Surya Prakash, Fang Wang, Timothy Stewart, 2009

机译：作为氟甲基亲核试剂的α-氟-α-硝基（苯基磺酰基）甲烷：查耳酮的高效立体选择性迈克尔加成

7. Исследование взаимодействия халконов и халконо-подандов с C- и N-нуклеофилами [O] . Валова, М. С., Овчинникова, И. Г., Забелина, О. Н., 2011

机译：查耳酮和查耳酮配体与C-和N-亲核试剂相互作用的研究

8. Extraction of Green River and Chattanooga Oil Shales with Strong Bases and Nucleophilic Displacement Reagents [R] . Robertson, R. E., Holmes, S. A. 1985

机译：用强碱和亲核置换试剂提取绿河和查塔努加油页岩