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Workgroup Report: Biomonitoring Study Design, Interpretation, and Communication—Lessons Learned and Path Forward

机译:工作组报告:生物监测研究设计,解释和交流-经验教训和前进方向

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摘要

Human biomonitoring investigations have provided data on a wide array of chemicals in blood and urine and in other tissues and fluids such as hair and human milk. These data have prompted questions such as a) What is the relationship between levels of environmental chemicals in humans and external exposures? b) What is the baseline or “background” level against which individual levels should be compared? and c) How can internal levels be used to draw conclusions about individual and/or population health? An interdisciplinary panel was convened for a 1-day workshop in November 2004 with the charge of focusing on three specific aspects of biomonitoring: characteristics of scientifically robust biomonitoring studies, interpretation of human biomonitoring data for potential risks to human health, and communication of results, uncertainties, and limitations of biomonitoring studies. In this report we describe the recommendations of the panel.
机译:人体生物监测研究提供了有关血液和尿液以及其他组织和液体(例如头发和人乳)中多种化学物质的数据。这些数据引发了以下问题:a)人类环境中化学物质的含量与外部暴露之间的关系是什么? b)应将个人水平与基准水平或“背景”水平进行比较? c)如何利用内部水平得出有关个人和/或人群健康的结论?在2004年11月召开了为期1天的研讨会的跨学科小组会议,其重点是生物监测的三个具体方面:科学可靠的生物监测研究的特征,对人类生物监测数据的解释对人类健康的潜在风险以及结果交流,生物监测研究的不确定性和局限性。在此报告中,我们描述了小组的建议。

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