Current Intelligence Bulletin 21. Trimellitic Anhydride (TMA)

摘要

The National Institute for Occupational Safety and Health (NIOSH) recommends that trimellitic anhydride (TMA) be handled as an extremely toxic agent in the workplace. Exposure to this compound may result in noncardiac pulmonary edema (apparently without benefit of pulmonary irritation warning), immunological sensitization, and irritation of the pulmonary tract, eyes, nose, and skin. There is no current Occupational Safety and Health Administration (OSHA) exposure standard for trimellitic anhydride. The Amoco Chemicals Corporation, the sole domestic producer, suggests a limit of 0.05 mg/m3 or less for susceptible individuals.