Report on Women Pharmaceutical Workers and Adverse Reproductive Outcomes

摘要

A reproductive history survey of past and current female employees of pharmaceutical laboratories (SIC-2934) was conducted using a retrospective cohort study design. A total of 191 laboratory workers and 318 comparisons participated in telephone interviews. A panel of physicians classified responses into categories of congenital malformation, perinatal illness, normal physiologic variant, and normal. The authors conclude that there was a significantly higher proportion of congenital malformations among children born to women employed in the laboratory area of a pharmaceutical research facility. The cluster was limited in time and results may have been biased by social and economic traits. In addition, the study was not a randomly selected population, but rather a self reported cluster of miscarriages and stillbirths.