New Chemical Analysis Methods Based on Redox Reactions Coupled with Chemiluminescence Measurements

摘要

The fundamental chemistry of metal-catalyzed reactions of nitrogen dioxide and nitric acid with organic and inorganic compounds has been studied. This chemistry forms the basis of the Redox Chemiluminescence Detector (RCD) for use with gas, liquid, and supercritical fluid chromatograph (SFC). Researchers investigated: (1) the potential of using gold-catalzed oxidations of organic compounds by NO2 for the synthesis of organic compounds, (2) the surface chemistry of NO2, NO, and O2 on single crystal samples of gold and platinum in high vacuum, and (3) catalytic reactions of nitrogen dioxide, using gold and other metals, for the selective formation of ionic species and subsequent detection of the ions using ionization detectors. Initial experiments have indicated that the GC version of the RCD can be easily adapted for use with SFC. Liquid phase reactions of nitric acid with organic compounds to form nitric oxide and subsequent detection of NO by chemiluminescence has been used to form the basis of a detector for liquid chromatography.