首页> 美国政府科技报告 >CRITICALLY CONTROLLED INHALATION STUDY OF PATHOGENESIS OF NEODYMIUM OXIDE IN MICE AND GUINEA PIGS
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CRITICALLY CONTROLLED INHALATION STUDY OF PATHOGENESIS OF NEODYMIUM OXIDE IN MICE AND GUINEA PIGS

机译:小鼠和豚鼠体内氧化钕发病机制的临床控制吸入研究

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This experiment was designed to evaluate the effects of an aerosol of stable neodymium oxide (Nd2O3) of a known particle size range and concentration on the lungs, other major organs, blood and body weight of mice and guinea pigs when administered over various periods of time up to 120 days.nIn order to accomplish this an inhalation system was constructed, and the aerosol produced was characterized concerning its particle size and concentration. The final experimental design was the outgrowth of a pilot intratracheal injection experiment conducted on guinea pigs and rats.

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