Experimental Louse-Borne Relapsing Fever in the Grivet Monkey, 'Cercopithecus aethiops'. III. Crisis Following Therapy.

摘要

Eight grivet monkeys infected with Borrelia recurrentis received tetracycline (12.5 mg/kg body weight) on the 3rd or 4th day of spirochetemia. Leukopenia, fever, hyperpnea, and tachycardia developed within 2 hours as spirochete counts fell to undetectable levels. These events closely simulated the crisis in human louse-borne relapsing fever in both timing and extent. (Author)