Identification of Hookworm Species in Ethiopia.

摘要

Adult hookworms were collected and identified to species following administration of single doses of bephenium hydroxynaphthoate to 132 subjects in Addis Ababa (103), Gondar (23), and Gambela (6). Six subjects were also given tetrachlorethylene. Contrary to the widely held assumption that Ancylostoma duodenale is the only hookworm of man in Ethiopia, the study revealed a great preponderance of Necator americanus in subjects whose infections were contracted in many different parts of the country. Tetrachlorethylene was more effective than bephenium against Necator in the six subjects given both drugs. The suggestion was made that some of the disappointment expressed by clinicians with the newer anthelmintics appearing in Ethiopia may stem from the fact that Necator infections normally require two or three times the dosage needed to effect cures of Ancylostoma infections. (Author)