Investigation of Crimean-Congo Hemorrhagic Fever and Hemorrhagic Fever with RenalSyndrome in Greece

摘要

During a 3 year and 2 month period, from April 1987 to June 1990, 3,067 humansera were tested for antibody to Hantaan and C-CHF viruses. The overall antibody prevalence rate was found to be 3,0% and 1,8% respectively. Animal serosurveys were conducted for antibody to C-CHF virus (goats and sheep) and for antibody to Hantaan virus (small mammals). The overall antibody prevalence rate was found to be 3.8% and 2,8% in goats and sheep respectively. High antibody titers to Hantaan virus were detected only in Apodemus flavicollis sera suggesting that Ap. flavicollis is the possible host of the virus. A Hantavirus was isolated from a severely MFRS ill patient. Serological comparison of the isolated virus to other Hantaviruses established it as a member of this group. Twenty HFRS cases have been serologically diagnosed. The disease was a severe form of HFRS with a mortality rate 15%. For C-CHF blood samples were obtained from patients with disease resembling C-CHF (60 patients) and from patients with other diseases. None of the patients was found to be infected with C-CHF virus. During May 1990, an inapparent C-CHF infection was serologically diagnosed.