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首页> 外文期刊>Physics in medicine and biology. >Organ dose calculations by Monte Carlo modeling of the updated VCH adult male phantom against idealized external proton exposure.
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Organ dose calculations by Monte Carlo modeling of the updated VCH adult male phantom against idealized external proton exposure.

机译:通过蒙特卡洛模型对理想的外部质子暴露进行更新的VCH成年男性体模的器官剂量计算。

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摘要

The voxel-based visible Chinese human (VCH) adult male phantom has offered a high-quality test bed for realistic Monte Carlo modeling in radiological dosimetry simulations. The phantom has been updated in recent effort by adding newly segmented organs, revising walled and smaller structures as well as recalibrating skeletal marrow distributions. The organ absorbed dose against external proton exposure was calculated at a voxel resolution of 2 x 2 x 2 mm(3) using the MCNPX code for incident energies from 20 MeV to 10 GeV and for six idealized irradiation geometries: anterior-posterior (AP), posterior-anterior (PA), left-lateral (LLAT), right-lateral (RLAT), rotational (ROT) and isotropic (ISO), respectively. The effective dose on the VCH phantom was derived in compliance with the evaluation scheme for the reference male proposed in the 2007 recommendations of the International Commission on Radiological Protection (ICRP). Algorithm transitions from the revised radiation and tissue weighting factors are accountable for approximately 90% and 10% of effective dose discrepancies in proton dosimetry, respectively. Results are tabulated in terms of fluence-to-dose conversion coefficients for practical use and are compared with data from other models available in the literature. Anatomical variations between various computational phantoms lead to dose discrepancies ranging from a negligible level to 100% or more at proton energies below 200 MeV, corresponding to the spatial geometric locations of individual organs within the body. Doses show better agreement at higher energies and the deviations are mostly within 20%, to which the organ volume and mass differences should be of primary responsibility. The impact of body size on dose distributions was assessed by dosimetry of a scaled-up VCH phantom that was resized in accordance with the height and total mass of the ICRP reference man. The organ dose decreases with the directionally uniform enlargement of voxels. Potential pathways to improve the VCH phantom have also been briefly addressed. This work pertains to VCH-based systematic multi-particle dose investigations and will contribute to comparative dosimetry studies of ICRP standardized voxel phantoms in the near future.
机译:基于体素的可见中国人(VCH)成年男性幻象为放射剂量学模拟中的逼真的蒙特卡洛建模提供了高质量的测试平台。幻影在最近的工作中得到了更新,增加了新分割的器官,修改了壁的和较小的结构以及重新校准了骨骼的分布。使用MCNPX代码针对20 MeV至10 GeV的入射能量以及六个理想的照射几何体:前-后(AP),以2 x 2 x 2 mm的体素分辨率计算出针对外部质子暴露的器官吸收剂量,前后(PA),左侧(LLAT),右侧(RLAT),旋转(ROT)和各向同性(ISO)。 VCH体模上的有效剂量是根据国际放射防护委员会(ICRP)2007年建议中提出的参考男性评估方案得出的。从修正的辐射和组织权重因子的算法转换分别占质子剂量学中有效剂量差异的约90%和10%。根据实际使用的通量-剂量转换系数将结果制成表格,并与文献中其他模型的数据进行比较。在低于200 MeV的质子能量下,各种计算体模之间的解剖变化会导致剂量差异范围从可忽略的水平到100%或更高,这对应于体内各个器官的空间几何位置。剂量在较高的能量下显示出更好的一致性,并且偏差大​​多在20%以内,器官的体积和质量差异应对此负主要责任。人体大小对剂量分布的影响是通过按比例放大的VCH体模的剂量学评估的,该体模根据ICRP参考人员的身高和总体重进行了调整。器官剂量随着体素的方向均匀增大而减小。改善VCH幻象的潜在途径也已简要讨论。这项工作涉及基于VCH的系统多颗粒剂量研究,并将在不久的将来为ICRP标准化体素体模的比较剂量学研究做出贡献。

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