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首页> 外文期刊>Physics in medicine and biology. >Optimization of the modelling of longitudinal dose distributions for double-scattered proton beams in a commercially-available treatment planning system
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Optimization of the modelling of longitudinal dose distributions for double-scattered proton beams in a commercially-available treatment planning system

机译:商用治疗计划系统中双散射质子束纵向剂量分布建模的优化

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摘要

The configuration of a treatment planning system (TPS) for double-scattering-based proton therapy requires many user inputs. Most of these are either gathered during the routine collection of commissioning data, or can be supplied by the equipment vendor; however, this is not true of all. In this study we developed a technique both to (a) expedite the extraction of those undetermined TPS parameters related to the range modulator wheels that can only otherwise be obtained by the time-consuming process of trial-and-error, and (b) demonstrate how, for a commonly-employed, commercially-available TPS, the judicious determination of such parameters can be used to optimize the resultant modelling of longitudinal dose distributions delivered by a double scattering proton therapy system. Our technique is simple to implement, robust in nature and also provides insight allowing parameters that must be contrived in that model to be related directly to physical aspects of the beam delivery system.
机译:用于基于双散射的质子治疗的治疗计划系统(TPS)的配置需要许多用户输入。其中大多数要么在例行调试数据收集期间收集,要么可以由设备供应商提供。但是,事实并非如此。在这项研究中,我们开发了一种技术(a)加快与范围调制器轮有关的那些未确定的TPS参数的提取,而这些参数只有通过耗时的反复试验才能获得,并且(b)证明对于常见的可商购的TPS,如何明智地确定此类参数可用于优化由双散射质子治疗系统提供的纵向剂量分布的最终建模。我们的技术易于实现,本质上很健壮,还提供了洞察力,使必须在该模型中设计的参数直接与光束传输系统的物理方面相关。

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