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A novel technique for VMAT QA with EPID in cine mode on a Varian TrueBeam linac

机译:在Varian TrueBeam直线加速器上以电影模式使用EPID进行VMAT QA的新技术

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Volumetric modulated arc therapy (VMAT) is a relatively new treatment modality for dynamic photon radiation therapy. Pre-treatment quality assurance (QA) is necessary and many efforts have been made to apply electronic portal imaging device (EPID)-based IMRT QA methods to VMAT. It is important to verify the gantry rotation speed during delivery as this is a new variable that is also modulated in VMAT. In this paper, we present a new technique to perform VMAT QA using an EPID. The method utilizes EPID cine mode and was tested on Varian TrueBeam in research mode. The cine images were acquired during delivery and converted to dose matrices after profile correction and dose calibration. A sub-arc corresponding to each cine image was extracted from the original plan and its portal image prediction was calculated. Several analyses were performed including 3D γ analysis (2D images + gantry angle axis), 2D γ analysis, and other statistical analyses. The method was applied to 21 VMAT photon plans of 3 photon energies. The accuracy of the cine image information was investigated. Furthermore, this method's sensitivity to machine delivery errors was studied. The pass rate (92.8 ± 1.4%) for 3D γ analysis was comparable to those from Delta4 system (99.9 ± 0.1%) under similar criteria (3%, 3 mm, 5% threshold and 2° angle to agreement) at 6 MV. The recorded gantry angle and start/stop MUs were found to have sufficient accuracy for clinical QA. Machine delivery errors can be detected through combined analyses of 3D γ, gantry angle, and percentage dose difference. In summary, we have developed and validated a QA technique that can simultaneously verify the gantry angle and delivered MLC fluence for VMAT treatment.This technique is efficient and its accuracy is comparable to other QA methods.
机译:体积调制电弧疗法(VMAT)是用于动态光子放射疗法的一种相对较新的治疗方式。预处理质量保证(QA)是必要的,并且已经进行了许多努力,以将基于电子门禁成像设备(EPID)的IMRT QA方法应用于VMAT。在交付过程中验证龙门架转速非常重要,因为这是一个新变量,也在VMAT中进行了调制。在本文中,我们提出了一种使用EPID执行VMAT QA的新技术。该方法利用EPID电影模式,并在研究模式下的Varian TrueBeam上进行了测试。电影图像在分娩过程中获取,并在轮廓校正和剂量校准后转换为剂量矩阵。从原始计划中提取与每个电影图像相对应的子弧,并计算其门户图像预测。进行了一些分析,包括3Dγ分析(2D图像+龙门角度轴),2Dγ分析和其他统计分析。该方法已应用于3个光子能量的21个VMAT光子计划。电影图像信息的准确性进行了调查。此外,研究了该方法对机器交付错误的敏感性。在6 MV下,在类似标准(3%,3 mm,5%阈值和2°一致角度)下,用于3Dγ分析的通过率(92.8±1.4%)与Delta4系统的通过率(99.9±0.1%)是可比的。发现记录的机架角度和开始/停止MU具有足够的临床QA准确性。可以通过对3Dγ,龙门角度和剂量差异百分比的组合分析来检测机器交付错误。总而言之,我们开发并验证了一种QA技术,该技术可以同时验证龙门角度并提供VLC处理的MLC通量,该技术有效且其准确性可与其他QA方法媲美。

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