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Experimental verification of dose calculation using the simplified Monte Carlo method with an improved initial beam model for a beam-wobbling system

机译:使用简化的蒙特卡洛方法和改进的光束摆动系统的初始光束模型进行剂量计算的实验验证

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摘要

A beam delivery system using a single-radius-beam-wobbling method has been used to form a conformal irradiation field for proton radiotherapy in Japan. A proton beam broadened by the beam-wobbling system provides a non-Gaussian distribution of projection angle different in two mutually orthogonal planes with a common beam central axis, at a certain position. However, the conventional initial beam model for dose calculations has been using an approximation of symmetric Gaussian angular distribution with the same variance in both planes (called here a Gaussian model with symmetric variance (GMSV)), instead of the accurate one. We have developed a more accurate initial beam model defined as a non-Gaussian model with asymmetric variance (NonGMAV), and applied it to dose calculations using the simplified Monte Carlo (SMC) method. The initial beam model takes into account the different distances of two beam-wobbling magnets from the iso-center and also the different amplitudes of kick angle given by each magnet. We have confirmed that the calculation using the SMC with NonGMAV reproduced the measured dose distribution formed in air by a mono-energetic proton beam passing through a square aperture collimator better than with the GMSV and with a Gaussian model with asymmetric variance (GMAV) in which different variances of angular distributions are used in the two mutually orthogonal planes. Measured dose distributions in a homogeneous phantom formed by a modulated proton beam passing through a range shifter and an L-shaped range compensator, were consistent with calculations using the SMC with GMAV and NonGMAV, but in disagreement with calculations using the SMC with GMSV. Measured lateral penumbrae in a lateral direction were reproduced better by calculations using the SMC with NonGMAV than by those with GMAV, when an aperture collimator with a smaller opening was used. We found that such a difference can be attributed to the non-Gaussian angular distribution of the initial beam at a lateral position for the beam-wobbling system. Calculations using the SMC with NonGMAV are effective to reproduce dose distributions formed by a beam-wobbling system more accurately than that with GMSV or that with GMAV.
机译:在日本,已经使用使用单半径光束摆动方法的束传输系统来形成用于质子放射治疗的保形辐射场。通过光束摆动系统加宽的质子束在特定位置处在具有共同的光束中心轴的两个相互正交的平面中提供了不同的投影角非高斯分布。然而,用于剂量计算的常规初始射束模型已经使用在两个平面中具有相同方差的对称高斯角分布的近似值(这里称为具有对称方差的高斯模型(GMSV)),而不是精确的模型。我们已经开发了一种更精确的初始射束模型,该模型被定义为具有非对称方差的非高斯模型(NonGMAV),并将其应用于使用简化蒙特卡洛(SMC)方法进行的剂量计算。初始射束模型考虑了两个摆动磁体与等中心点的不同距离,以及每个磁体给出的突跳角的不同幅度。我们已经证实,使用带有NonGMAV的SMC进行的计算可以再现通过方孔准直仪的单能质子束在空气中形成的测得剂量分布,优于GMSV和非对称方差高斯模型(GMAV),其中在两个相互正交的平面中使用不同的角度分布方差。调制质子束通过测距仪和L形测距补偿器形成的均匀幻象中测得的剂量分布与使用GMAV和NonGMAV的SMC进行的计算一致,但与使用GMSV的SMC进行的计算不一致。当使用孔径较小的光阑准直器时,通过使用带有NonGMAV的SMC进行的计算,与使用GMAV的SMC进行的计算相比,可以更好地重现横向测量的半影。我们发现,这种差异可归因于光束摆动系统在横向位置处初始光束的非高斯角分布。与GMSV或GMAV相比,使用NonGMAV的SMC进行的计算可以更有效地重现由波束摆动系统形成的剂量分布。

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