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A novel depth-of-interaction block detector for positron emission tomography using a dichotomous orthogonal symmetry decoding concept

机译:一种使用二分正交对称解码概念的正电子发射断层扫描的新型相互作用深度块检测器

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摘要

Conventionally, a dual-end depth-of-interaction (DOI) block detector readout requires two two-dimensional silicon photomultiplier (SiPM) arrays, one on top and one on the bottom, to define the XYZ positions. However, because both the top and bottom SiPM arrays are reading the same pixels, this creates information redundancy. We propose a dichotomous orthogonal symmetric (DOS) dual-end readout block detector design, which removes this redundancy by reducing the number of SiPMs and still achieves XY and DOI (Z) decoding for positron emission tomography (PET) block detector. Reflecting films are used within the block detector to channel photons going to the top of the block to go only in the X direction, and photons going to the bottom are channeled along the Y direction. Despite the unidirectional channeling on each end, the top readout provides both X and Y information using two one-dimensional SiPM arrays instead of a two-dimensional SiPM array; similarly, the bottom readout also provides both X and Y information with just two one-dimensional SiPM arrays. Thus, a total of four one-dimensional SiPM arrays (4 x N SiPMs) are used to decode the XYZ positions of the firing pixels instead of two two-dimensional SiPM arrays (2 x N x N SiPMs), reducing the number of SiPM arrays per block from 2N(2) to 4 N for PET/MR or PET/CT systems. Moreover, the SiPM arrays on one end can be replaced by two regular photomultiplier tubes (PMTs), so that a block needs only 2 N SiPMs + 2 half-PMTs; this hybrid-DOS DOI block detector can be used in PET/CT systems. Monte Carlo simulations were carried out to study the performance of our DOS DOI block detector design, including the XY-decoding quality, energy resolution, and DOI resolution. Both BGO and LSO scintillators were studied. We found that 4 mm pixels were well decoded for 5 x 5 BGO and 9 x 9 LSO arrays with 4 to 5 mm DOI resolution and 16-20% energy resolution. By adding light-channel decoding, we modified the DOS design to a high-resolution design, which resolved scintillator pixels smaller than the SiPM dimensions. Detector pixels of 2.4 mm were decoded for 8 x 8 BGO and 15 x 15 LSO arrays with 5 mm DOI resolution and 20-23% energy resolution. Time performance was also studied for the 8 x 8 BGO and 15 x 15 LSO HR-DOS arrays. The timing resolution for the corner and central crystals is 986 +/- 122 ps and 1.89 +/- 0.17 mu s respectively with BGO, 137 +/- 42 ps and 458 +/- 67 ps respectively with LSO. Monte Carlo simulations with GATE/Geant4 demonstrated the feasibility of our DOS DOI block detector design. In conclusion, our novel design achieved good performance except the time performance while using fewer SiPMs and supporting electronic channels than the current non-DOI PET detectors. This novel design can significantly reduce the cost, heat, and readout complexity of DOI block detectors for PET/MR/CT systems that don't require the time-of-flight capability.
机译:按照惯例,双端交互深度(DOI)块检测器读数需要两个二维硅光电倍增器(SiPM)阵列,一个在顶部,一个在底部,以定义XYZ位置。但是,由于顶部和底部SiPM阵列都在读取相同的像素,因此会产生信息冗余。我们提出了一种二分法正交对称(DOS)双端读出块检测器设计,该设计通过减少SiPM的数量消除了这种冗余,并且仍然实现了正电子发射断层扫描(PET)块检测器的XY和DOI(Z)解码。块探测器中使用反射膜来引导到达块顶部的光子,使其仅沿X方向传播,到达底部的光子,沿Y方向被引导。尽管两端都有单向通道,但顶部读数使用两个一维SiPM阵列而不是二维SiPM阵列来提供X和Y信息。同样,底部读数也仅通过两个一维SiPM阵列提供X和Y信息。因此,代替两个二维SiPM阵列(2 x N x N SiPM),总共使用了四个一维SiPM阵列(4 x N SiPM)来解码触发像素的XYZ位置,从而减少了SiPM的数量对于PET / MR或PET / CT系统,每个块的阵列范围从2N(2)到4N。而且,一端的SiPM阵列可以用两个常规的光电倍增管(PMT)代替,因此一个模块仅需要2 N个SiPM + 2个半PMT。该混合DOS DOI块检测器可用于PET / CT系统。进行了蒙特卡洛模拟以研究我们的DOS DOI块检测器设计的性能,包括XY解码质量,能量分辨率和DOI分辨率。 BGO和LSO闪烁体均已进行了研究。我们发现,对于4 x 5 mm DOI分辨率和16-20%能量分辨率的5 x 5 BGO和9 x 9 LSO阵列,可以很好地解码4 mm像素。通过添加光通道解码,我们将DOS设计修改为高分辨率设计,从而解决了小于SiPM尺寸的闪烁体像素。对于8 x 8 BGO和15 x 15 LSO阵列(具有5 mm DOI分辨率和20-23%的能量分辨率),解码了2.4 mm的检测器像素。还研究了8 x 8 BGO和15 x 15 LSO HR-DOS阵列的时间性能。角晶体和中心晶体的时序分辨率在BGO中分别为986 +/- 122 ps和1.89 +/- 0.17μs,在LSO中分别为137 +/- 42 ps和458 +/- 67 ps。用GATE / Geant4进行的蒙特卡洛仿真证明了我们的DOS DOI块检测器设计的可行性。总之,与目前的非DOI PET探测器相比,我们的新颖设计除了时间性能外,还具有良好的性能,同时使用更少的SiPM和支持的电子通道。这种新颖的设计可以显着降低不需要飞行时间的PET / MR / CT系统的DOI块检测器的成本,热量和读出复杂度。

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