'Schizophrenia past Clozapine': Reasons for Clozapine Discontinuation, Mortality, and Alternative Antipsychotic Prescribing

摘要

Introduction: The clinical records of 190 patients with schizophrenia who discontinued clozapine between 1990 and 2012 in the county of Northamptonshire were examined, in an attempt to answer the following questions. Why do patients stop clozapine? What do physicians prescribe as an alternative? What is the mortality in this patient group?