Effects of combining tactile with visual and spatial cues in conditioned place preference

摘要

Previous research provides little information about variables that determine which elements of contextual cues gain associative control over behavior in the conditioned place preference (CPP) procedure. These studies examined the effect of external visual-spatial cues on CPP when tactile cues served as the conditioned stimuli. DBA/2J mice were trained in the dark (Experiment 1) or light (Experiment 2) using unbiased procedures in which the spatial location of an ethanol-paired tactile cue during training was relevant (two-compartment procedure) or irrelevant (one-compartment procedure). All groups developed CPP, but it was weakest after one-compartment training in the light.