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Trichoepithelioma, not Basal cell carcinoma, in an 8-year-old child.

机译:一名8岁儿童的毛发上皮细胞瘤,而非基底细胞癌。

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This was a difficult case. The biopsy was initially interpreted as "basophilic cellular tumor" with a recommendation for reexcision to ensure complete histologic evaluation and removal of the lesion. Mohs surgery at this site was appropriate given the anatomic location of the lesion. The immunohistochemical stains demonstrated mixed features of trichoepithelioma (TE) and basal cell carcinoma (BCC). I reported CD 10 and Bcl-2 stains in the original pathology report. The CD 10 stain highlighted the peritumoral stroma focally but was predominantly negative in tumor lobules suggestive of TE, but the peritumoral stroma was negative for CD 10 in other areas. The Bcl-2 staining was diffusely positive within lobules of tumor, suggestive of BCC.
机译:这是一个困难的情况。活检最初被解释为“嗜碱性细胞性肿瘤”,建议再次切除以确保完整的组织学评估和病变清除。考虑到病变的解剖位置,在该部位进行莫氏手术是合适的。免疫组织化学染色显示了毛发上皮瘤(TE)和基底细胞癌(BCC)的混合特征。我在原始病理报告中报告了CD 10和Bcl-2染色。 CD 10染色可局部突出肿瘤周围基质,但在提示TE的肿瘤小叶中主要呈阴性,而在其他区域,肿瘤周围基质CD 10阴性。 Bcl-2染色在肿瘤小叶内弥漫阳性,提示BCC。

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