LUMACAFTOR/IVACAFTOR IN CF PATIENTS WITH HOMOZYGOUS P.PHE508DEL MUTATIONS: IMPROVING PERSONALIZED MEDICINE UTILIZING INTESTINAL ORGANOIDS

Pouw J. N.; de Winter-de Groot K. M.; Berkers G.; van Mourik P.; de Graaf E.; Vries R.; Beekman J.; Clevers H. C.; van der Ent C. K.

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LUMACAFTOR/IVACAFTOR IN CF PATIENTS WITH HOMOZYGOUS P.PHE508DEL MUTATIONS: IMPROVING PERSONALIZED MEDICINE UTILIZING INTESTINAL ORGANOIDS

机译：具有均质P.PHE508DEL突变的CF患者的LUMACAFTOR / IVACAFTOR：利用肠道有机体改善个性化药物

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《Pediatric Pulmonology 》 |2016年第51期| 共1页
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Pouw J. N.; de Winter-de Groot K. M.; Berkers G.; van Mourik P.; de Graaf E.; Vries R.; Beekman J.; Clevers H. C.; van der Ent C. K.;
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正文语种 eng
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1. LUMACAFTOR/IVACAFTOR IN CF PATIENTS WITH HOMOZYGOUS P.PHE508DEL MUTATIONS: IMPROVING PERSONALIZED MEDICINE UTILIZING INTESTINAL ORGANOIDS [J] . Pouw J. N., de Winter-de Groot K. M., Berkers G., Pediatric Pulmonology . 2016 ,第Suppla51期

机译：具有均质P.PHE508DEL突变的CF患者的LUMACAFTOR / IVACAFTOR：利用肠道有机体改善个性化药物
2. COMBINATION LUMACAFTOR/IVACAFTOR THERAPY IMPROVES INFLAMMATORY BIOMARKERS IN PATIENTS WITH CF HOMOZYGOUS FOR THE F508DEL-CFTR MUTATION [J] . Sullivan J. C., Accurso F. J., Marigowda G., Pediatric Pulmonology . 2016 ,第Suppla51期

机译：氟尿嘧啶/伊伐替丁联合治疗可改善CF均质性CF突变患者的炎症生物标志物
3. COMBINATION LUMACAFTOR/IVACAFTOR THERAPY IMPROVES INFLAMMATORY BIOMARKERS IN PATIENTS WITH CF HOMOZYGOUS FOR THE F508DEL-CFTR MUTATION [J] . Sullivan J. C., Accurso F. J., Marigowda G., Pediatric Pulmonology . 2016 ,第Suppla45期

机译：组合Lumacaftor / Ivacafacter治疗改善了CF纯合的炎性生物标志物，用于F508DEL-CFTR突变
4. Ivacaftor induces Pseudomonas aeruginosa population proteome changes in the airways of CF patients with G551D mutations [C] . Xia Wu, Katherine B. Hisert, Jayanthi Garudathri, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：Ivacafacter诱导铜绿假单胞菌蛋白酶蛋白质组蛋白质组变化，CF患者G551D突变患者
5. The investigation of quality of life, perceived disease severity, and adherence in patients with the G551D mutation receiving Ivacaftor therapy [D] . Hathorne, Heather 2015

机译：接受IVACafacor治疗的G551D突变患者的生活质量，感知疾病严重程度和依从性的调查
6. Corticosteroid use and increased CXCR2 levels on leukocytes are associated with lumacaftor/ivacaftor discontinuation in cystic fibrosis patients homozygous for the F508del CFTR mutation [O] . Kerstin Pohl, David P. Nichols, Jennifer L. Taylor-Cousar, -1

机译：对于F508del CFTR突变纯合的囊性纤维化患者使用皮质类固醇激素和白细胞CXCR2水平升高与lumacaftor / ivacaftor停药有关
7. S11.4 Relationship between organoid swelling and improvement of CFTR function in patients with cystic fibrosis homozygous for the F508del mutation receiving lumacaftor-ivacaftor [O] . S.Y. Graeber, P. van Mourik, A.M. Vonk, 2020

机译：S11.4有机膜肿胀与CFTR功能改善C508del突变术治疗Lumacaftor-Ivacaftor的关系

LUMACAFTOR/IVACAFTOR IN CF PATIENTS WITH HOMOZYGOUS P.PHE508DEL MUTATIONS: IMPROVING PERSONALIZED MEDICINE UTILIZING INTESTINAL ORGANOIDS

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