Spirometry in 5-year-olds-validation of current guidelines and the relation with asthma.

摘要

Introduction. Spirometry is more frequently measured in younger children. Our primary aim was to validate 2005 ATS-ERS Task Force standards for spirometry in adults and older children among a population of 5-year-old children. Our secondary aim was to relate spirometry to asthma symptoms.METHODS: Children were participants in a longitudinal cohort study where asthma symptoms and spirometry were assessed. RESULTS: Of the 827 children assessed, spirometry was obtained in 638 (85 with wheeze). A back-extrapolated volume/FVC ratio of <5% was achieved in 99% of children, the best two FVC were /=3 sec, whereas 80% had an FET of >/=1 sec. All criteria (including FET >/=1 s and FVC