Reactivity of arylic carbanions generated by reductive cleavage of C-N bond of N,N-dimethylanilines

摘要

Phenyl-substituted N,N-dimethylanilines, synthesized by Suzuki coupling reactions in good yields, are transformed to their corresponding arylic carbanions by reductive C-N cleavage with lithium at room temperature. These carbanions react with various electrophiles affording the corresponding ipso-substituted products with absolute regioselectivity. [References: 39]